Lamprey Variable Lymphocyte Receptor: Difference between revisions
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[[ | [[Image:3g3a biol unitsurf.png|370px|left|thumb| Lamprey Variable Lymphocyte Receptor in complex with a protein antigen ([[3g3a]])]] | ||
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{{Structure | {{Structure | ||
|PDB= 3e6j |SIZE= | |PDB= 3e6j |SIZE=350|SCENE=Lamprey_Variable_Lymphocyte_Receptor/Defaultjmol/3|CAPTION= Lamprey Variable Lymphocyte Receptor in complex with a trisaccharide antigen ([[3e6j]]), resolution 1.67Å (<scene name='Lamprey_Variable_Lymphocyte_Receptor/Defaultjmol/3'>initial scene</scene>) | ||
|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= | ||
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e6j OCA], [http://www.ebi.ac.uk/pdbsum/3e6j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3e6j RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e6j OCA], [http://www.ebi.ac.uk/pdbsum/3e6j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3e6j RCSB]</span> | ||
}} | }} | ||
===Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide=== | ===Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide=== | ||
< | <scene name='Lamprey_Variable_Lymphocyte_Receptor/Ncrainbow/1'>N->C rainbow of the protein</scene> | ||
<scene name='Lamprey_Variable_Lymphocyte_Receptor/Leucines_highlighted/1'>Leucines highlighed in cyan</scene> | |||
==About these Structures== | ==About these Structures== | ||
Lamprey [[Variable Lymphocyte Receptors|VLRs]] are members of the [[Leucine-rich repeat]] (LRR) family of diverse proteins. [[Variable Lymphocyte Receptors|Variable lymphocyte receptors]] are involved in the adaptative immune response.<br> | |||
[[3e6j]] is a single chain structure of sequence from [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6J OCA]. | [[3e6j]] is a single chain structure of sequence from [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6J OCA]. | ||
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[[3g39]] is a single chain structure with sequence from [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G39 OCA]. | [[3g39]] is a single chain structure with sequence from [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G39 OCA]. | ||
[[3m18]] is a 2 chain structure with sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M18 OCA]. | |||
[[3m19]] is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Petromyzon_marinus Petromyzon marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M19 OCA]. | |||
==3D structures of variable lymphocyte receptor== | |||
[[Variable lymphocyte receptor]] | |||
==References and Notes== | ==References and Notes== | ||
<ref group="xtra">PMID:18818359</ref><ref group="xtra">PMID: 19543291</ref><references group="xtra"/> | <ref group="xtra">PMID:18818359</ref><ref group="xtra">PMID: 19543291</ref><ref group="xtra">PMID: 20616002</ref><references group="xtra"/> | ||
==See Also== | ==See Also== | ||
* [[Variable Lymphocyte Receptors]] | * [[Variable Lymphocyte Receptors]] | ||
*[[leucine-rich repeat|Leucine-rich Repeat Proteins]] | |||
* [[Antibody]] | * [[Antibody]] | ||
* [[Forkhead box family]] | |||
==Additional Literature== | ==Additional Literature== | ||
<ref group="xtra">PMID: 15241406</ref><ref group="xtra">PMID: 17192264</ref><ref group="xtra">PMID: 20482318</ref><ref group="xtra">PMID: 20660361</ref><ref group="xtra">PMID: 19840917</ref><references group="xtra"/> | <ref group="xtra">PMID: 21293377</ref><ref group="xtra">PMID: 15241406</ref><ref group="xtra">PMID: 17192264</ref><ref group="xtra">PMID: 20482318</ref><ref group="xtra">PMID: 20660361</ref><ref group="xtra">PMID: 19840917</ref><references group="xtra"/> | ||
==External Resources== | ==External Resources== | ||
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[[Category: Variable lymphocyte receptor]] | [[Category: Variable lymphocyte receptor]] | ||
[[Category: Vlr]] | [[Category: Vlr]] | ||
[[Category:Topic Page]] | |||