3n01: Difference between revisions

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{{Seed}}
[[Image:3n01.jpg|left|200px]]


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==Crystal structure of an abridged form of the mature ectodomain of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512/IA-2 at pH 8.5==
The line below this paragraph, containing "STRUCTURE_3n01", creates the "Structure Box" on the page.
<StructureSection load='3n01' size='340' side='right'caption='[[3n01]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3n01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N01 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_3n01|  PDB=3n01  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n01 OCA], [https://pdbe.org/3n01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n01 RCSB], [https://www.ebi.ac.uk/pdbsum/3n01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n01 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTPRN_HUMAN PTPRN_HUMAN] Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.<ref>PMID:8144912</ref> <ref>PMID:8641276</ref>


===Crystal structure of an abridged form of the mature ectodomain of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512/IA-2 at pH 8.5===
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
== References ==
==About this Structure==
<references/>
3N01 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N01 OCA].
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:18048354</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ermacora, M R.]]
[[Category: Large Structures]]
[[Category: Jakoncic, J.]]
[[Category: Ermacora MR]]
[[Category: Poskus, E.]]
[[Category: Jakoncic J]]
[[Category: Primo, M E.]]
[[Category: Poskus E]]
[[Category: Autoimmunity]]
[[Category: Primo ME]]
[[Category: Diabetes]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Ia-2]]
[[Category: Ica-512]]
[[Category: Protein-tyrosine phosphatase]]
[[Category: Proteolysis]]
[[Category: Receptor]]
[[Category: Transmembrane protein]]
 
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Retrieved from "https://proteopedia.org/3n01"