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[[Image:1z72.gif|left|200px]]<br /><applet load="1z72" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1z72, resolution 1.45&Aring;" />
'''Structure of a putative transcriptional regulator from Streptococcus pneumoniae'''<br />


==About this Structure==
==Structure of a putative transcriptional regulator from Streptococcus pneumoniae==
1Z72 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA].
<StructureSection load='1z72' size='340' side='right'caption='[[1z72]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Streptococcus pneumoniae tigr4]]
<table><tr><td colspan='2'>[[1z72]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z72 FirstGlance]. <br>
[[Category: Abdullah, J.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
[[Category: Cuff, M.E.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Joachimiak, A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [https://pdbe.org/1z72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB], [https://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z72 ProSAT], [https://www.topsan.org/Proteins/MCSG/1z72 TOPSAN]</span></td></tr>
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
</table>
[[Category: Zhou, M.]]
== Function ==
[[Category: ACY]]
[https://www.uniprot.org/uniprot/A0A0H2UP67_STRPN A0A0H2UP67_STRPN] Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).[PIRNR:PIRNR003170]
[[Category: MG]]
== Evolutionary Conservation ==
[[Category: mcsg]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: midwest center for structural genomics]]
Check<jmol>
[[Category: protein structure initiative]]
  <jmolCheckbox>
[[Category: psi]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z72_consurf.spt"</scriptWhenChecked>
[[Category: streptococcus pneumoniae]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: structural genomics]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: transcription regulator]]
  </jmolCheckbox>
[[Category: transcriptional regulator]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z72 ConSurf].
 
<div style="clear:both"></div>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:49:05 2008''
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Abdullah J]]
[[Category: Cuff ME]]
[[Category: Joachimiak A]]
[[Category: Zhou M]]

Latest revision as of 05:03, 17 October 2024

Structure of a putative transcriptional regulator from Streptococcus pneumoniae

1z72, resolution 1.45Å

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