2e37: Difference between revisions

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New page: left|200px<br /><applet load="2e37" size="350" color="white" frame="true" align="right" spinBox="true" caption="2e37, resolution 2.30Å" /> '''Structure of TT0471 ...
 
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[[Image:2e37.jpg|left|200px]]<br /><applet load="2e37" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2e37, resolution 2.30&Aring;" />
'''Structure of TT0471 protein from Thermus thermophilus'''<br />


==About this Structure==
==Structure of TT0471 protein from Thermus thermophilus==
2E37 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E37 OCA].
<StructureSection load='2e37' size='340' side='right'caption='[[2e37]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
[[Category: L-lactate dehydrogenase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2e37]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E37 FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
[[Category: Lokanath, N.K.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e37 OCA], [https://pdbe.org/2e37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e37 RCSB], [https://www.ebi.ac.uk/pdbsum/2e37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e37 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e37 TOPSAN]</span></td></tr>
[[Category: NAD]]
</table>
[[Category: SO4]]
== Function ==
[[Category: nad/nadp binding dehydrogenase]]
[https://www.uniprot.org/uniprot/LDH_THET8 LDH_THET8]  
[[Category: national project on protein structural and functional analyses]]
== Evolutionary Conservation ==
[[Category: nppsfa]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: oxidoreductase]]
Check<jmol>
[[Category: riken structural genomics/proteomics initiative]]
  <jmolCheckbox>
[[Category: rsgi]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e37_consurf.spt"</scriptWhenChecked>
[[Category: structural genomics]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e37 ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:57:58 2008''
==See Also==
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Lokanath NK]]
Retrieved from "https://proteopedia.org/2e37"