2l6z: Difference between revisions
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New page: '''Unreleased structure''' The entry 2l6z is ON HOLD Authors: Gamsjaeger, R., Matthews, J.M. Description: haddock model of GATA1NF:Lmo2LIM2-Ldb1LID with FOG ''Page seeded by [http://o... |
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==haddock model of GATA1NF:Lmo2LIM2-Ldb1LID with FOG== | |||
<StructureSection load='2l6z' size='340' side='right'caption='[[2l6z]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2l6z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L6Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l6z OCA], [https://pdbe.org/2l6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l6z RCSB], [https://www.ebi.ac.uk/pdbsum/2l6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l6z ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GATA1_MOUSE GATA1_MOUSE] Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells.<ref>PMID:2276623</ref> <ref>PMID:8206977</ref> <ref>PMID:8524811</ref> <ref>PMID:15173587</ref> <ref>PMID:16888089</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Crossley M]] | |||
[[Category: Dastmalchi S]] | |||
[[Category: Gamsjaeger R]] | |||
[[Category: Mackay JP]] | |||
[[Category: Matthews JM]] | |||
[[Category: Stokes PH]] | |||
[[Category: Wienert B]] | |||
[[Category: Wilkinson-White L]] | |||
Latest revision as of 06:54, 1 May 2024
haddock model of GATA1NF:Lmo2LIM2-Ldb1LID with FOG
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