2xzz: Difference between revisions
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New page: '''Unreleased structure''' The entry 2xzz is ON HOLD Authors: Vollmar, M., Krysztofinska, E., Krojer, T., Yue, W.W., Cooper, C., Kavanagh, K., Allerston, C., Chaikuad, A., Von Delft, F.... |
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==Crystal structure of the human transglutaminase 1 beta-barrel domain== | |||
<StructureSection load='2xzz' size='340' side='right'caption='[[2xzz]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2xzz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XZZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzz OCA], [https://pdbe.org/2xzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xzz RCSB], [https://www.ebi.ac.uk/pdbsum/2xzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xzz ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN] Lamellar ichthyosis;Self-healing collodion baby;Bathing suit ichthyosis;Acral self-healing collodion baby;Congenital non-bullous ichthyosiform erythroderma. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Allerston C]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Cooper C]] | |||
[[Category: Edwards A]] | |||
[[Category: Kavanagh K]] | |||
[[Category: Krojer T]] | |||
[[Category: Krysztofinska E]] | |||
[[Category: Oppermann U]] | |||
[[Category: Vollmar M]] | |||
[[Category: Weigelt J]] | |||
[[Category: Yue WW]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 08:06, 23 August 2023
Crystal structure of the human transglutaminase 1 beta-barrel domain
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