3pfy: Difference between revisions

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{{Seed}}
[[Image:3pfy.jpg|left|200px]]


<!--
==The catalytic domain of human OTUD5==
The line below this paragraph, containing "STRUCTURE_3pfy", creates the "Structure Box" on the page.
<StructureSection load='3pfy' size='340' side='right'caption='[[3pfy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3pfy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PFY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.702&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3pfy|  PDB=3pfy  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pfy OCA], [https://pdbe.org/3pfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pfy RCSB], [https://www.ebi.ac.uk/pdbsum/3pfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pfy ProSAT]</span></td></tr>
 
</table>
===The catalytic domain of human OTUD5===
== Function ==
 
[https://www.uniprot.org/uniprot/OTUD5_HUMAN OTUD5_HUMAN] Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).<ref>PMID:17991829</ref> <ref>PMID:22245969</ref>
 
== References ==
==About this Structure==
<references/>
3PFY is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PFY OCA].  
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ubiquitinyl hydrolase 1]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Asinas, A E.]]
[[Category: Asinas AE]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Crombet, L.]]
[[Category: Crombet L]]
[[Category: Dhe-Paganon, S.]]
[[Category: Dhe-Paganon S]]
[[Category: Dong, A.]]
[[Category: Dong A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Walker JR]]
[[Category: Walker, J R.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Hydrolase]]
[[Category: Peptidase c65 otubain]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:44:51 2010''

Latest revision as of 09:33, 30 October 2024

The catalytic domain of human OTUD5

3pfy, resolution 1.70Å

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