3ong: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (12 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways== | |||
<StructureSection load='3ong' size='340' side='right'caption='[[3ong]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ong]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ONG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ong FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ong OCA], [https://pdbe.org/3ong PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ong RCSB], [https://www.ebi.ac.uk/pdbsum/3ong PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ong ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UBA2_YEAST UBA2_YEAST] The dimeric enzyme acts as a SMT3 E1 ligase. It mediates ATP-dependent activation of SMT3 and formation of a thioester with a conserved cysteine residue on AOS1. | |||
==See Also== | |||
*[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | |||
*[[3D structures of Ubiquitin activating enzyme|3D structures of Ubiquitin activating enzyme]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Huang DT]] | |||
[[Category: Hunt HW]] | |||
[[Category: Miller DW]] | |||
[[Category: Schulman BA]] | |||
[[Category: Seyedin SN]] | |||
[[Category: Taherbhoy AM]] | |||
[[Category: Wang J]] | |||
Latest revision as of 10:35, 21 February 2024
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
| ||||||||||||
