3pz7: Difference between revisions
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New page: '''Unreleased structure''' The entry 3pz7 is ON HOLD Authors: Liu, Y.T., Wang, J.W., Chen, L, Wu, J.W. Description: Molecular basis of WNT activation via the DIX-domain protein CCD1 '... |
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==Crystal structure of Ccd1-DIX domain== | |||
<StructureSection load='3pz7' size='340' side='right'caption='[[3pz7]], [[Resolution|resolution]] 2.44Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZ7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.441Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pz7 OCA], [https://pdbe.org/3pz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pz7 RCSB], [https://www.ebi.ac.uk/pdbsum/3pz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pz7 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DIXC1_HUMAN DIXC1_HUMAN] Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.<ref>PMID:15262978</ref> <ref>PMID:21189423</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen L]] | |||
[[Category: Liu YT]] | |||
[[Category: Wang JW]] | |||
[[Category: Wu JW]] | |||
Latest revision as of 13:35, 1 March 2024
Crystal structure of Ccd1-DIX domain
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