3pzf: Difference between revisions
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New page: '''Unreleased structure''' The entry 3pzf is ON HOLD Authors: Lovell, Scott, Battaile, Kevin P., An, Chunju, Michel, Kristin Description: 1.75A resolution structure of Serpin-2 from An... |
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==1.75A resolution structure of Serpin-2 from Anopheles gambiae== | |||
<StructureSection load='3pzf' size='340' side='right'caption='[[3pzf]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pzf OCA], [https://pdbe.org/3pzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pzf RCSB], [https://www.ebi.ac.uk/pdbsum/3pzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pzf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SP2_ANOGA SP2_ANOGA] Serine protease inhibitor that functions in the melanization-mediated immune response (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing the activation of phenoloxidases through the inhibiting of serine proteases CLIPB9 and CLIPB10, negatively regulates melanization in the hemolymph (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing melanization, has a detrimental role during P.berghei parasite mediated-infection and invasion of the mosquito midgut (PubMed:16113656).<ref>PMID:16113656</ref> <ref>PMID:20953892</ref> <ref>PMID:21465556</ref> <ref>PMID:25525260</ref> <ref>PMID:33045027</ref> <ref>PMID:33520733</ref> | |||
==See Also== | |||
*[[Serpin 3D structures|Serpin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Anopheles gambiae]] | |||
[[Category: Large Structures]] | |||
[[Category: An C]] | |||
[[Category: Battaile KP]] | |||
[[Category: Lovell S]] | |||
[[Category: Michel K]] | |||
Latest revision as of 10:44, 21 February 2024
1.75A resolution structure of Serpin-2 from Anopheles gambiae
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