3q0u: Difference between revisions
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New page: '''Unreleased structure''' The entry 3q0u is ON HOLD Authors: Flipo, M., Desroses, M., Diri , B., Carette, X., Lens, Z., Rucktooa, P., Leroux, F., Piveteau, C., Demirkaya, F., Locht, C.... |
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==EthR from Mycobacterium tuberculosis in complex with compound BDM31379== | |||
<StructureSection load='3q0u' size='340' side='right'caption='[[3q0u]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q0u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LL3:2-PHENYL-1-{4-[3-(THIOPHEN-2-YL)-1,2,4-OXADIAZOL-5-YL]PIPERIDIN-1-YL}ETHANONE'>LL3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0u OCA], [https://pdbe.org/3q0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0u RCSB], [https://www.ebi.ac.uk/pdbsum/3q0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | |||
==See Also== | |||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Baulard A]] | |||
[[Category: Brodin P]] | |||
[[Category: Carette X]] | |||
[[Category: Christophe T]] | |||
[[Category: Demirkaya F]] | |||
[[Category: Deprez B]] | |||
[[Category: Desroses M]] | |||
[[Category: Dirie B]] | |||
[[Category: Flipo M]] | |||
[[Category: Jeon HK]] | |||
[[Category: Lens Z]] | |||
[[Category: Leroux F]] | |||
[[Category: Locht C]] | |||
[[Category: Piveteau C]] | |||
[[Category: Rucktooa P]] | |||
[[Category: Villeret V]] | |||
[[Category: Willand N]] | |||
Latest revision as of 10:45, 21 February 2024
EthR from Mycobacterium tuberculosis in complex with compound BDM31379
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