1en4: Difference between revisions

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[[Image:1en4.png|left|200px]]


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==CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT==
The line below this paragraph, containing "STRUCTURE_1en4", creates the "Structure Box" on the page.
<StructureSection load='1en4' size='340' side='right'caption='[[1en4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1en4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_1en4|  PDB=1en4  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en4 OCA], [https://pdbe.org/1en4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en4 RCSB], [https://www.ebi.ac.uk/pdbsum/1en4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en4 ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT===
== Function ==
 
[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11141052}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 11141052 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en4_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11141052}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1en4]] is a 4 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en4 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Superoxide Dismutase]]
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:11141052</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Baker, E N.]]
[[Category: Baker EN]]
[[Category: Edwards, R A.]]
[[Category: Edwards RA]]
[[Category: Jameson, G B.]]
[[Category: Jameson GB]]
[[Category: Whittaker, J W.]]
[[Category: Whittaker JW]]
[[Category: Whittaker, M M.]]
[[Category: Whittaker MM]]
[[Category: Manganese superoxide dismutase]]
[[Category: Mutant]]
[[Category: Oxidoreductase]]
[[Category: Proton shuttle]]
[[Category: Q146h]]

Latest revision as of 07:04, 7 February 2024

CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT

1en4, resolution 2.00Å

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