2g7y: Difference between revisions

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[[Image:2g7y.png|left|200px]]


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==Human Cathepsin S with inhibitor CRA-16981==
The line below this paragraph, containing "STRUCTURE_2g7y", creates the "Structure Box" on the page.
<StructureSection load='2g7y' size='340' side='right'caption='[[2g7y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2g7y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G7Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MO9:(1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL+MORPHOLINE-4-CARBOXYLATE'>MO9</scene></td></tr>
{{STRUCTURE_2g7y|  PDB=2g7y  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g7y OCA], [https://pdbe.org/2g7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g7y RCSB], [https://www.ebi.ac.uk/pdbsum/2g7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g7y ProSAT]</span></td></tr>
 
</table>
===Human Cathepsin S with inhibitor CRA-16981===
== Function ==
 
[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2g7y]] is a 2 chain structure of [[Cathepsin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7Y OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g7/2g7y_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g7y ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cathepsin]]
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
[[Category: Cathepsin S]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Somoza, J R.]]
[[Category: Large Structures]]
[[Category: 16981]]
[[Category: Somoza JR]]
[[Category: Cysteine protease]]
[[Category: Hydrolase]]
[[Category: Papain]]
Retrieved from "https://proteopedia.org/2g7y"