3b6u: Difference between revisions

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[[Image:3b6u.png|left|200px]]


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==Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP==
The line below this paragraph, containing "STRUCTURE_3b6u", creates the "Structure Box" on the page.
<StructureSection load='3b6u' size='340' side='right'caption='[[3b6u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3b6u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6U FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
{{STRUCTURE_3b6u|  PDB=3b6u  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6u OCA], [https://pdbe.org/3b6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6u RCSB], [https://www.ebi.ac.uk/pdbsum/3b6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6u ProSAT]</span></td></tr>
 
</table>
===Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP===
== Function ==
 
[https://www.uniprot.org/uniprot/KIF3B_HUMAN KIF3B_HUMAN] Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[3b6u]] is a 2 chain structure of [[Kinesin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6U OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6u_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b6u ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kinesin]]
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M.]]
[[Category: Bochkarev A]]
[[Category: Landry, R.]]
[[Category: Edwards AM]]
[[Category: Park, H.]]
[[Category: Landry R]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Shen, Y.]]
[[Category: Shen Y]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom M]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Zhu, H.]]
[[Category: Zhu H]]
[[Category: Adp]]
[[Category: Atp-binding]]
[[Category: Coiled coil]]
[[Category: Kinesin]]
[[Category: Microtubule]]
[[Category: Motor domain]]
[[Category: Motor protein]]
[[Category: Nucleotide-binding]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/3b6u"