1fx8: Difference between revisions

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[[Image:1fx8.png|left|200px]]


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==CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL==
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<StructureSection load='1fx8' size='340' side='right'caption='[[1fx8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fx8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The May 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aquaporin''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_5 10.2210/rcsb_pdb/mom_2014_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FX8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_1fx8|  PDB=1fx8  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx8 OCA], [https://pdbe.org/1fx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fx8 RCSB], [https://www.ebi.ac.uk/pdbsum/1fx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx8 ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL===
== Function ==
 
[https://www.uniprot.org/uniprot/GLPF_ECOLI GLPF_ECOLI] Transporter of glycerol across the cytoplasmic membrane, with limited permeability to water and small uncharged compounds such as polyols.
 
== Evolutionary Conservation ==
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==About this Structure==
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[[1fx8]] is a 1 chain structure of [[Ion channels]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX8 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fx8 ConSurf].
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==See Also==
==See Also==
*[[Ion channels]]
*[[Aquaporin 3D structures|Aquaporin 3D structures]]
 
*[[Ion channels 3D structures|Ion channels 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:11039922</ref><references group="xtra"/>
</StructureSection>
[[Category: Aquaporin]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Fu, D.]]
[[Category: Large Structures]]
[[Category: Libson, A.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Miercke, L J.W.]]
[[Category: Fu D]]
[[Category: Nollert, P.]]
[[Category: Libson A]]
[[Category: Stroud, R M.]]
[[Category: Miercke LJW]]
[[Category: Weitzman, C.]]
[[Category: Nollert P]]
[[Category: Glycerol-conducting membrane channel protein]]
[[Category: Stroud RM]]
[[Category: Membrane protein]]
[[Category: Weitzman C]]