2qyi: Difference between revisions

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[[Image:2qyi.png|left|200px]]


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==Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin==
The line below this paragraph, containing "STRUCTURE_2qyi", creates the "Structure Box" on the page.
<StructureSection load='2qyi' size='340' side='right'caption='[[2qyi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qyi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QYI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
{{STRUCTURE_2qyi|  PDB=2qyi  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qyi OCA], [https://pdbe.org/2qyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qyi RCSB], [https://www.ebi.ac.uk/pdbsum/2qyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qyi ProSAT]</span></td></tr>
 
</table>
===Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin===
== Function ==
 
[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2qyi]] is a 4 chain structure of [[Chymotrypsin Inhibitor]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYI OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/2qyi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qyi ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Chymotrypsin Inhibitor]]
*[[Chymotrypsin inhibitor 3D structures|Chymotrypsin inhibitor 3D structures]]
 
*[[Trypsin 3D structures|Trypsin 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:16081330</ref><references group="xtra"/>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Psophocarpus tetragonolobus]]
[[Category: Psophocarpus tetragonolobus]]
[[Category: Dasgupta, J.]]
[[Category: Dasgupta J]]
[[Category: Dattagupta, J K.]]
[[Category: Dattagupta JK]]
[[Category: Khamrui, S.]]
[[Category: Khamrui S]]
[[Category: Sen, U.]]
[[Category: Sen U]]
[[Category: Bovine trypsin]]
[[Category: Calcium]]
[[Category: Complex]]
[[Category: Digestion]]
[[Category: Hydrolase]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Metal-binding]]
[[Category: P1 mutant]]
[[Category: Protease]]
[[Category: Protease inhibitor]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease inhibitor]]
[[Category: Trypsin inhibitor]]
[[Category: Zymogen]]

Latest revision as of 05:28, 17 October 2024

Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin

2qyi, resolution 2.60Å

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