3q2t: Difference between revisions
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==Crystal Structure of CFIm68 RRM/CFIm25/RNA complex== | |||
<StructureSection load='3q2t' size='340' side='right'caption='[[3q2t]], [[Resolution|resolution]] 3.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q2t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.061Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2t OCA], [https://pdbe.org/3q2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2t RCSB], [https://www.ebi.ac.uk/pdbsum/3q2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CPSF6_HUMAN CPSF6_HUMAN] Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:21295486</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Coseno M]] | |||
[[Category: Doublie S]] | |||
[[Category: Gilmartin GM]] | |||
[[Category: Yang Q]] | |||
Latest revision as of 11:31, 14 March 2024
Crystal Structure of CFIm68 RRM/CFIm25/RNA complex
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