3p5p: Difference between revisions

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[[Image:3p5p.jpg|left|200px]]


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==Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate==
The line below this paragraph, containing "STRUCTURE_3p5p", creates the "Structure Box" on the page.
<StructureSection load='3p5p' size='340' side='right'caption='[[3p5p]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3p5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P5P FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.816&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3C:2-(METHYL{2-[(1S,4AS,8AS)-5,5,8A-TRIMETHYL-2-METHYLIDENEDECAHYDRONAPHTHALEN-1-YL]ETHYL}AMINO)ETHYL+TRIHYDROGEN+DIPHOSPHATE'>A3C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3p5p|  PDB=3p5p  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p5p OCA], [https://pdbe.org/3p5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p5p RCSB], [https://www.ebi.ac.uk/pdbsum/3p5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p5p ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate===
== Function ==
 
[https://www.uniprot.org/uniprot/TASY_TAXBR TASY_TAXBR] Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton.
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_21160477}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 21160477 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21160477}}
 
==About this Structure==
[[3p5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA].  
 
==Reference==
<ref group="xtra">PMID:21160477</ref><references group="xtra"/>
[[Category: Taxadiene synthase]]
[[Category: Taxus brevifolia]]
[[Category: Taxus brevifolia]]
[[Category: Christianson, D W.]]
[[Category: Christianson DW]]
[[Category: Koksal, M.]]
[[Category: Koksal M]]
[[Category: 3-azacopalyl diphosphate]]
[[Category: Biosynthesis of paclitaxel]]
[[Category: Class i and ii terpene cyclase fold]]
[[Category: Ddxxd motif]]
[[Category: Diterpene cyclase]]
[[Category: Lyase]]
[[Category: Nse/dte motif]]

Latest revision as of 10:38, 21 February 2024

Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate

3p5p, resolution 1.82Å

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