3h0q: Difference between revisions

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[[Image:3h0q.png|left|200px]]


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==Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 3==
The line below this paragraph, containing "STRUCTURE_3h0q", creates the "Structure Box" on the page.
<StructureSection load='3h0q' size='340' side='right'caption='[[3h0q]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3h0q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H0Q FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B37:4-({4-[(2-METHYLQUINOLIN-6-YL)METHYL]PIPERIDIN-1-YL}CARBONYL)-2-PHENYLQUINOLINE'>B37</scene></td></tr>
{{STRUCTURE_3h0q| PDB=3h0q |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h0q OCA], [https://pdbe.org/3h0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h0q RCSB], [https://www.ebi.ac.uk/pdbsum/3h0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h0q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACAC_YEAST ACAC_YEAST] Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.<ref>PMID:6108218</ref> <ref>PMID:6103540</ref> <ref>PMID:8943372</ref> <ref>PMID:10757783</ref> <ref>PMID:12730220</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/3h0q_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h0q ConSurf].
<div style="clear:both"></div>


===Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 3===
==See Also==
 
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
 
== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 20219367 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_20219367}}
 
==About this Structure==
[[3h0q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0Q OCA].
 
==Reference==
<ref group="xtra">PMID:20219367</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Zhang, H.]]
[[Category: Zhang H]]
[[Category: Acetyl-coa carboxylase]]
[[Category: Carboxyltransferase]]
[[Category: Inhibitor]]
[[Category: Ligase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3h0q"