3q0m: Difference between revisions
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==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb== | |||
<StructureSection load='3q0m' size='340' side='right'caption='[[3q0m]], [[Resolution|resolution]] 2.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q0m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.705Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0m OCA], [https://pdbe.org/3q0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0m RCSB], [https://www.ebi.ac.uk/pdbsum/3q0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hall TMT]] | |||
[[Category: Lu G]] | |||
Latest revision as of 10:44, 21 February 2024
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb
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