3q7f: Difference between revisions
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==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1== | |||
<StructureSection load='3q7f' size='340' side='right'caption='[[3q7f]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q7f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CX:(2S)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3CX</scene>, <scene name='pdbligand=ED2:N-BENZYL-N-(2-{(4-CYANOPHENYL)[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]AMINO}ETHYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE'>ED2</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7f OCA], [https://pdbe.org/3q7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7f RCSB], [https://www.ebi.ac.uk/pdbsum/3q7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7f ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q55S71_CRYNB Q55S71_CRYNB] | |||
==See Also== | |||
*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cryptococcus neoformans var. grubii H99]] | |||
[[Category: Large Structures]] | |||
[[Category: Beese LS]] | |||
[[Category: Hast MA]] | |||
Latest revision as of 10:46, 21 February 2024
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1
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