3qb5: Difference between revisions

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'''Unreleased structure'''


The entry 3qb5 is ON HOLD
==Human C3PO complex in the presence of MnSO4==
 
<StructureSection load='3qb5' size='340' side='right'caption='[[3qb5]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
Authors: Ye, X., Huang, N., Liu, Y., Paroo, Z., Chen, S., Zhang, H., Liu, Q.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3qb5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QB5 FirstGlance]. <br>
Description: Human C3PO complex in the presence of MnSO4
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qb5 OCA], [https://pdbe.org/3qb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qb5 RCSB], [https://www.ebi.ac.uk/pdbsum/3qb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qb5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>  Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen S]]
[[Category: Huang N]]
[[Category: Liu Q]]
[[Category: Liu Y]]
[[Category: Paroo Z]]
[[Category: Ye X]]
[[Category: Zhang H]]
Retrieved from "https://proteopedia.org/3qb5"