3qgp: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 3qgp is ~~ON HOLD~~

==Crystal structure of IsdI in complex with heme and cyanide==

== Structural highlights ==

<table><tr><td colspan='2'>[[3qgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGP OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=3QGP FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=3qgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgp OCA], [https://pdbe.org/3qgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgp RCSB], [https://www.ebi.ac.uk/pdbsum/3qgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgp ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/HDOX2_STAAN HDOX2_STAAN] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272]<ref>PMID:18713745</ref> <ref>PMID:20180905</ref>

~~Authors~~: ~~Ukpabi, Georgia N~~., Murphy~~, Michael E.P.~~

==See Also==

*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]

~~Description~~: ~~Crystal structure of IsdI in complex with heme and cyanide~~

*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Staphylococcus aureus subsp. aureus N315]]

[[Category: Murphy MEP]]

[[Category: Ukpabi GN]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 3qgp is ON HOLD
+==Crystal structure of IsdI in complex with heme and cyanide==
+<StructureSection load='3qgp' size='340' side='right'caption='[[3qgp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3qgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGP FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgp OCA], [https://pdbe.org/3qgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgp RCSB], [https://www.ebi.ac.uk/pdbsum/3qgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HDOX2_STAAN HDOX2_STAAN] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272]<ref>PMID:18713745</ref> <ref>PMID:20180905</ref>
-Authors: Ukpabi, Georgia N., Murphy, Michael E.P.
+==See Also==
+*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]
-Description: Crystal structure of IsdI in complex with heme and cyanide
+*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Staphylococcus aureus subsp. aureus N315]]
+[[Category: Murphy MEP]]
+[[Category: Ukpabi GN]]