3pmn: Difference between revisions

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[[Image:3pmn.jpg|left|200px]]


<!--
==ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site==
The line below this paragraph, containing "STRUCTURE_3pmn", creates the "Structure Box" on the page.
<StructureSection load='3pmn' size='340' side='right'caption='[[3pmn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3pmn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1GC:2-DEOXY-5-O-[(R)-HYDROXY{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]METHYL}PHOSPHORYL]GUANOSINE'>1GC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_3pmn|  PDB=3pmn  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmn OCA], [https://pdbe.org/3pmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pmn RCSB], [https://www.ebi.ac.uk/pdbsum/3pmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pmn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>


===ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site===
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_21233421}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 21233421 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_21233421}}
 
==About this Structure==
[[3pmn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMN OCA].
 
==Reference==
<ref group="xtra">PMID:21233421</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bebenek, K.]]
[[Category: Large Structures]]
[[Category: Kunkel, T A.]]
[[Category: Bebenek K]]
[[Category: Pedersen, L C.]]
[[Category: Kunkel TA]]
[[Category: Pedersen LC]]

Latest revision as of 10:41, 21 February 2024

ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site

3pmn, resolution 2.20Å

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