3qj7: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qj7 is ON HOLD Authors: Reddy, M.C.M., Bruning, J.B., Harshbarger, W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) Description: C... |
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==Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP== | |||
<StructureSection load='3qj7' size='340' side='right'caption='[[3qj7]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qj7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QJ7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.504Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qj7 OCA], [https://pdbe.org/3qj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qj7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qj7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity). | |||
==See Also== | |||
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Bruning JB]] | |||
[[Category: Harshbarger W]] | |||
[[Category: Reddy MCM]] | |||
[[Category: Sacchettini JC]] | |||
Latest revision as of 11:47, 14 March 2024
Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP
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