3qj7: Difference between revisions

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'''Unreleased structure'''


The entry 3qj7 is ON HOLD
==Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP==
<StructureSection load='3qj7' size='340' side='right'caption='[[3qj7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qj7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QJ7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.504&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qj7 OCA], [https://pdbe.org/3qj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qj7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qj7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).


Authors: Reddy, M.C.M., Bruning, J.B., Harshbarger, W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
==See Also==
 
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
Description: Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Bruning JB]]
[[Category: Harshbarger W]]
[[Category: Reddy MCM]]
[[Category: Sacchettini JC]]
Retrieved from "https://proteopedia.org/3qj7"