2egw: Difference between revisions

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New page: left|200px<br /><applet load="2egw" size="350" color="white" frame="true" align="right" spinBox="true" caption="2egw, resolution 2.80Å" /> '''Crystal structure of...
 
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[[Image:2egw.jpg|left|200px]]<br /><applet load="2egw" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2egw, resolution 2.80&Aring;" />
'''Crystal structure of rRNA methyltransferase with SAH ligand'''<br />


==About this Structure==
==Crystal structure of rRNA methyltransferase with SAH ligand==
2EGW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGW OCA].  
<StructureSection load='2egw' size='340' side='right'caption='[[2egw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2egw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egw OCA], [https://pdbe.org/2egw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egw RCSB], [https://www.ebi.ac.uk/pdbsum/2egw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egw ProSAT], [https://www.topsan.org/Proteins/RSGI/2egw TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2egw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2egw ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bessho, Y.]]
[[Category: Bessho Y]]
[[Category: Dong, X.]]
[[Category: Dong X]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: SAH]]
[[Category: m3u]]
[[Category: methyltransferase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: pua domain]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rna methyltransferase]]
[[Category: rrna modification]]
[[Category: rsgi]]
[[Category: rsme]]
[[Category: sah]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:45:22 2008''

Latest revision as of 13:49, 13 March 2024

Crystal structure of rRNA methyltransferase with SAH ligand

2egw, resolution 2.80Å

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