3lox: Difference between revisions

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[[Image:3lox.jpg|left|200px]]


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==HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound==
The line below this paragraph, containing "STRUCTURE_3lox", creates the "Structure Box" on the page.
<StructureSection load='3lox' size='340' side='right'caption='[[3lox]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lox]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MCX:(1R,2S,5S)-N-[(2S,3R)-4-AMINO-1-CYCLOBUTYL-3-HYDROXY-4-OXOBUTAN-2-YL]-6,6-DIMETHYL-3-{3-METHYL-N-[(1-METHYLCYCLOHEXYL)CARBAMOYL]-L-VALYL}-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE'>MCX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3lox|  PDB=3lox  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lox OCA], [https://pdbe.org/3lox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lox RCSB], [https://www.ebi.ac.uk/pdbsum/3lox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lox ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9ELS8_9HEPC Q9ELS8_9HEPC]


===HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound===
==See Also==
 
*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
 
*[[Virus protease 3D structures|Virus protease 3D structures]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_20303756}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 20303756 is the PubMed ID number.
[[Category: Hepatitis C virus genotype 1a]]
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_20303756}}
[[Category: Prongay AJ]]
 
==About this Structure==
[[3lox]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOX OCA].
 
==Reference==
<ref group="xtra">PMID:20303756</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1a]]
[[Category: Prongay, A J.]]

Latest revision as of 06:40, 3 April 2024

HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound

3lox, resolution 2.65Å

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