3q2l: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3q2l.jpg|left|200px]]


<!--
==Mouse E-cadherin EC1-2 V81D mutant==
The line below this paragraph, containing "STRUCTURE_3q2l", creates the "Structure Box" on the page.
<StructureSection load='3q2l' size='340' side='right'caption='[[3q2l]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3q2l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2L FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_3q2l|  PDB=3q2l  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2l OCA], [https://pdbe.org/3q2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2l RCSB], [https://www.ebi.ac.uk/pdbsum/3q2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).


===Mouse E-cadherin EC1-2 V81D mutant===
==See Also==
 
*[[Cadherin 3D structures|Cadherin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3q2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermomicrobium_roseum Thermomicrobium roseum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2L OCA].
[[Category: Large Structures]]
 
[[Category: Mus musculus]]
==Reference==
[[Category: Harrison OJ]]
<ref group="xtra">PMID:21300292</ref><references group="xtra"/>
[[Category: Jin X]]
[[Category: Thermomicrobium roseum]]
[[Category: Shapiro L]]
[[Category: Harrison, O J.]]
[[Category: Jin, X.]]
[[Category: Shapiro, L.]]

Latest revision as of 11:30, 14 March 2024

Mouse E-cadherin EC1-2 V81D mutant

3q2l, resolution 2.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=3q2l&oldid=4095512"