Im2: Difference between revisions
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Im2 is the [[Colicin Immunity Protein]] for [[Colicin E2]], produced by the cell at the same time to protect itself from the [[DNase Activity]] of the cytotoxic domain of ColE2. It is released when the [[Colicin]] binds to a cell surface receptor of a target cell. | Im2 is the [[Colicin Immunity Protein]] for [[Colicin E2]], produced by the cell at the same time to protect itself from the [[DNase Activity]] of the cytotoxic domain of ColE2. It is released when the [[Colicin]] binds to a cell surface receptor of a target cell. | ||
Im2 is also capable of binding to [[Colicin E9]], which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of colicin E9 to Im2. | Im2 is also capable of binding to [[Colicin E9]], which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of <scene name='Im2/Cole9frag/1'>colicin E9</scene> to <scene name='Im2/Im2/1'>Im2</scene>. | ||
<Structure load='2wpt' size=' | <Structure load='2wpt' size='350' frame='true' align='right' caption='Im2 bound to ColE9' scene= Im2/Noligands/1 /> | ||
==3D structures of colicin-E2 immunitiy protein== | |||
[[Colicin Immunity Protein]] | |||
