3q9c: Difference between revisions

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[[Image:3q9c.jpg|left|200px]]


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==Crystal Structure of H159A APAH complexed with N8-acetylspermidine==
The line below this paragraph, containing "STRUCTURE_3q9c", creates the "Structure Box" on the page.
<StructureSection load='3q9c' size='340' side='right'caption='[[3q9c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3q9c]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplana_ramosa Mycoplana ramosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q9C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Q9C:N-{4-[(3-AMINOPROPYL)AMINO]BUTYL}ACETAMIDE'>Q9C</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3q9c|  PDB=3q9c  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q9c OCA], [https://pdbe.org/3q9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q9c RCSB], [https://www.ebi.ac.uk/pdbsum/3q9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q9c ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of H159A APAH complexed with N8-acetylspermidine===
== Function ==
 
[https://www.uniprot.org/uniprot/APAH_MYCRA APAH_MYCRA] Involved in polyamine metabolism. Catalyzes the deacetylation of various acetylated polyamines such as N-acetylputrescine, N-acetylcadaverine, N(1)-acetylspermine, N(1)-acetylspermidine and N(8)-acetylspermidine (PubMed:8824626, PubMed:3207420). In vitro, is also able to deacetylate L-Lys(epsilon-acetyl)coumarin, but has very low activity towards the larger tetrapeptide N-acetyl-L-Arg-L-His-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)coumarin (PubMed:21268586).<ref>PMID:21268586</ref> <ref>PMID:3207420</ref> <ref>PMID:8824626</ref>
 
== References ==
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<references/>
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</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_21268586}}
 
==About this Structure==
[[3q9c]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycoplana_ramosa Mycoplana ramosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q9C OCA].  
 
==Reference==
<ref group="xtra">PMID:21268586</ref><references group="xtra"/>
[[Category: Mycoplana ramosa]]
[[Category: Mycoplana ramosa]]
[[Category: Christianson, D W.]]
[[Category: Christianson DW]]
[[Category: Lombardi, P M.]]
[[Category: Lombardi PM]]

Latest revision as of 11:38, 14 March 2024

Crystal Structure of H159A APAH complexed with N8-acetylspermidine

3q9c, resolution 2.30Å

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