3qwp: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qwp is ON HOLD Authors: Dong, A., Dombrovski, L., Li, Y., Wernimont, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Wu, H.... |
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==Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1== | |||
<StructureSection load='3qwp' size='340' side='right'caption='[[3qwp]], [[Resolution|resolution]] 1.53Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qwp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwp OCA], [https://pdbe.org/3qwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwp RCSB], [https://www.ebi.ac.uk/pdbsum/3qwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwp ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SMYD3_HUMAN SMYD3_HUMAN] Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.<ref>PMID:15235609</ref> <ref>PMID:22419068</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Dombrovski L]] | |||
[[Category: Dong A]] | |||
[[Category: Edwards AM]] | |||
[[Category: Li Y]] | |||
[[Category: Min J]] | |||
[[Category: Weigelt J]] | |||
[[Category: Wernimont A]] | |||
[[Category: Wu H]] | |||
Latest revision as of 12:01, 14 March 2024
Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1
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