3qyb: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qyb is ON HOLD Authors: Park, SY Description: X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain |
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==X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain== | |||
<StructureSection load='3qyb' size='340' side='right'caption='[[3qyb]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QYB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qyb OCA], [https://pdbe.org/3qyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qyb RCSB], [https://www.ebi.ac.uk/pdbsum/3qyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qyb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBCD4_HUMAN TBCD4_HUMAN] May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.<ref>PMID:15971998</ref> <ref>PMID:18771725</ref> <ref>PMID:22908308</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Park SY]] | |||
[[Category: Shoelson SE]] | |||
Latest revision as of 10:50, 21 February 2024
X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain
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