2eam: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /><applet load="2eam" size="350" color="white" frame="true" align="right" spinBox="true" caption="2eam" /> '''Solution structure of the N-terminal SAM-dom... |
No edit summary |
||
| (14 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Solution structure of the N-terminal SAM-domain of a human putative 47 kDa protein== | ||
<StructureSection load='2eam' size='340' side='right'caption='[[2eam]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2eam]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EAM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eam OCA], [https://pdbe.org/2eam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eam RCSB], [https://www.ebi.ac.uk/pdbsum/2eam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eam ProSAT], [https://www.topsan.org/Proteins/RSGI/2eam TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ANS1B_HUMAN ANS1B_HUMAN] Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.<ref>PMID:15862129</ref> <ref>PMID:15347684</ref> Isoform 3 can regulate global protein synthesis by altering nucleolar numbers (By similarity).<ref>PMID:15862129</ref> <ref>PMID:15347684</ref> Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing.<ref>PMID:15862129</ref> <ref>PMID:15347684</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/2eam_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eam ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Goroncy | [[Category: Goroncy AK]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Saito K]] | |||
[[Category: Saito | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 18:48, 29 May 2024
Solution structure of the N-terminal SAM-domain of a human putative 47 kDa protein
| ||||||||||||
