1wpu: Difference between revisions

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[[Image:1wpu.png|left|200px]]


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==Crystal Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA==
The line below this paragraph, containing "STRUCTURE_1wpu", creates the "Structure Box" on the page.
<StructureSection load='1wpu' size='340' side='right'caption='[[1wpu]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1wpu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WPU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1wpu|  PDB=1wpu  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wpu OCA], [https://pdbe.org/1wpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wpu RCSB], [https://www.ebi.ac.uk/pdbsum/1wpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wpu ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA===
== Function ==
 
[https://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15242603}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 15242603 is the PubMed ID number.
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/1wpu_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15242603}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1wpu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPU OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wpu ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:15242603</ref><ref group="xtra">PMID:15273277</ref><references group="xtra"/>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Kumar, P K.R.]]
[[Category: Large Structures]]
[[Category: Kumarevel, T S.]]
[[Category: Kumar PKR]]
[[Category: Mizuno, H.]]
[[Category: Kumarevel TS]]
[[Category: Antitermination]]
[[Category: Mizuno H]]
[[Category: Hutp]]
[[Category: Hutp-rna complex]]
[[Category: Rna binding]]
[[Category: Transcription regulation]]
[[Category: Transcription/rna complex]]

Latest revision as of 07:57, 25 October 2023

Crystal Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA

1wpu, resolution 1.48Å

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