2j5b: Difference between revisions

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[[Image:2j5b.png|left|200px]]


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==Structure of the Tyrosyl tRNA synthetase from Acanthamoeba polyphaga Mimivirus complexed with tyrosynol==
The line below this paragraph, containing "STRUCTURE_2j5b", creates the "Structure Box" on the page.
<StructureSection load='2j5b' size='340' side='right'caption='[[2j5b]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2j5b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_polyphaga_mimivirus Acanthamoeba polyphaga mimivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J5B FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TYE:4-[(2S)-2-AMINO-3-HYDROXYPROPYL]PHENOL'>TYE</scene></td></tr>
{{STRUCTURE_2j5b| PDB=2j5b |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5b OCA], [https://pdbe.org/2j5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j5b RCSB], [https://www.ebi.ac.uk/pdbsum/2j5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_MIMIV SYY_MIMIV] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity).<ref>PMID:15486256</ref> <ref>PMID:16510997</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j5b ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF THE TYROSYL TRNA SYNTHETASE FROM ACANTHAMOEBA POLYPHAGA MIMIVIRUS COMPLEXED WITH TYROSYNOL===
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_17855524}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 17855524 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_17855524}}
 
==About this Structure==
[[2j5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_polyphaga_mimivirus Acanthamoeba polyphaga mimivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5B OCA].
 
==Reference==
<ref group="xtra">PMID:17855524</ref><ref group="xtra">PMID:16510997</ref><references group="xtra"/>
[[Category: Acanthamoeba polyphaga mimivirus]]
[[Category: Acanthamoeba polyphaga mimivirus]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Abergel, C.]]
[[Category: Abergel C]]
[[Category: Claverie, J M.]]
[[Category: Claverie JM]]
[[Category: Giege, R.]]
[[Category: Giege R]]
[[Category: Rudinger-Thirion, J.]]
[[Category: Rudinger-thirion J]]
[[Category: Atp-binding]]
[[Category: Ligase]]
[[Category: Protein biosynthesis]]

Latest revision as of 06:41, 1 May 2024

Structure of the Tyrosyl tRNA synthetase from Acanthamoeba polyphaga Mimivirus complexed with tyrosynol

2j5b, resolution 2.20Å

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