2e7v: Difference between revisions
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New page: left|200px<br /><applet load="2e7v" size="350" color="white" frame="true" align="right" spinBox="true" caption="2e7v, resolution 1.92Å" /> '''Crystal structure of... |
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== | ==Crystal structure of SEA domain of transmembrane protease from Mus musculus== | ||
<StructureSection load='2e7v' size='340' side='right'caption='[[2e7v]], [[Resolution|resolution]] 1.92Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2e7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7V FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7v OCA], [https://pdbe.org/2e7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7v RCSB], [https://www.ebi.ac.uk/pdbsum/2e7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7v ProSAT], [https://www.topsan.org/Proteins/RSGI/2e7v TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TM11D_MOUSE TM11D_MOUSE] May play some biological role in the host defense system on the mucous membrane, independently of, or in cooperation with other substances in airway mucous or bronchial secretions (By similarity). Isoform 2 may play a key role in regulating adrenal proliferation by specifically cleaving N-POMC. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7v_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7v ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Chen L]] | |||
[[Category: Chen | [[Category: Hori-Takemoto C]] | ||
[[Category: Hori-Takemoto | [[Category: Kishishita S]] | ||
[[Category: Kishishita | [[Category: Liu ZJ]] | ||
[[Category: Liu | [[Category: Murayama K]] | ||
[[Category: Murayama | [[Category: Shirozu M]] | ||
[[Category: Wang BC]] | |||
[[Category: Shirozu | [[Category: Xie Y]] | ||
[[Category: Wang | [[Category: Yokoyama S]] | ||
[[Category: Xie | |||
[[Category: Yokoyama | |||
Latest revision as of 13:49, 13 March 2024
Crystal structure of SEA domain of transmembrane protease from Mus musculus
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