2qer: Difference between revisions

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New page: left|200px<br /><applet load="2qer" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qer, resolution 2.17Å" /> '''Crystal structure of...
 
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[[Image:2qer.jpg|left|200px]]<br /><applet load="2qer" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2qer, resolution 2.17&Aring;" />
'''Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro'''<br />


==About this Structure==
==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro==
2QER is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ALA:'>ALA</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QER OCA].
<StructureSection load='2qer' size='340' side='right'caption='[[2qer]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
[[Category: Cryptosporidium parvum iowa ii]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2qer]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QER FirstGlance]. <br>
[[Category: Amani, M.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
[[Category: Arrowsmith, C.H.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Artz, J.D.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qer OCA], [https://pdbe.org/2qer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qer RCSB], [https://www.ebi.ac.uk/pdbsum/2qer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qer ProSAT]</span></td></tr>
[[Category: Bochkarev, A.]]
</table>
[[Category: Edwards, A.M.]]
== Function ==
[[Category: Hassanali, A.]]
[https://www.uniprot.org/uniprot/A3FQ68_CRYPI A3FQ68_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
[[Category: Hills, T.]]
== Evolutionary Conservation ==
[[Category: Hui, R.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Kozieradzki, I.]]
Check<jmol>
[[Category: Lew, J.]]
  <jmolCheckbox>
[[Category: Lin, L.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qe/2qer_consurf.spt"</scriptWhenChecked>
[[Category: SGC, Structural.Genomics.Consortium.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Schapira, M.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Sundstrom, M.]]
  </jmolCheckbox>
[[Category: Vedadi, M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qer ConSurf].
[[Category: Wasney, G.]]
<div style="clear:both"></div>
[[Category: Weigelt, J.]]
__TOC__
[[Category: Wernimont, A.K.]]
</StructureSection>
[[Category: Zhao, Y.]]
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: ALA]]
[[Category: Large Structures]]
[[Category: GOL]]
[[Category: Amani M]]
[[Category: SO4]]
[[Category: Arrowsmith CH]]
[[Category: cryptosporidium]]
[[Category: Artz JD]]
[[Category: cyclophilin]]
[[Category: Bochkarev A]]
[[Category: malaria]]
[[Category: Edwards AM]]
[[Category: parvum]]
[[Category: Hassanali A]]
[[Category: sgc]]
[[Category: Hills T]]
[[Category: structural genomics]]
[[Category: Hui R]]
[[Category: structural genomics consortium]]
[[Category: Kozieradzki I]]
 
[[Category: Lew J]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:32:44 2008''
[[Category: Lin L]]
[[Category: Schapira M]]
[[Category: Sundstrom M]]
[[Category: Vedadi M]]
[[Category: Wasney G]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]
[[Category: Zhao Y]]

Latest revision as of 11:30, 30 August 2023

Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro

2qer, resolution 2.17Å

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