2ea1: Difference between revisions

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[[Image:2ea1.png|left|200px]]


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==Crystal structure of Ribonuclease I from Escherichia coli COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE==
The line below this paragraph, containing "STRUCTURE_2ea1", creates the "Structure Box" on the page.
<StructureSection load='2ea1' size='340' side='right'caption='[[2ea1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ea1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EA1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GPG:GUANYLYL-2,5-PHOSPHOGUANOSINE'>GPG</scene></td></tr>
{{STRUCTURE_2ea1| PDB=2ea1 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ea1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ea1 OCA], [https://pdbe.org/2ea1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ea1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ea1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ea1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNI_ECOLI RNI_ECOLI] One of the few RNases that cleaves the phosphodiester bond between any two nucleotide. Shows a preference for cytidylic or guanylic acid.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/2ea1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ea1 ConSurf].
<div style="clear:both"></div>


===Crystal structure of Ribonuclease I from Escherichia coli COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11368513}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11368513 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11368513}}
 
==About this Structure==
[[2ea1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EA1 OCA].
 
==Reference==
<ref group="xtra">PMID:11368513</ref><ref group="xtra">PMID:2541256</ref><references group="xtra"/>
[[Category: Enterobacter ribonuclease]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Lim, L W.]]
[[Category: Large Structures]]
[[Category: Lim, R W.]]
[[Category: Lim LW]]
[[Category: Padmanabhan, S.]]
[[Category: Lim RW]]
[[Category: Pan, J.]]
[[Category: Padmanabhan S]]
[[Category: Zhou, K.]]
[[Category: Pan J]]
[[Category: Hydrolase]]
[[Category: Zhou K]]
[[Category: Protein-gpg complex]]
Retrieved from "https://proteopedia.org/2ea1"