1nti: Difference between revisions

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[[Image:1nti.png|left|200px]]


<!--
==RDC-refined NMR structure of bovine Acyl-coenzyme A Binding Protein, ACBP==
The line below this paragraph, containing "STRUCTURE_1nti", creates the "Structure Box" on the page.
<StructureSection load='1nti' size='340' side='right'caption='[[1nti]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1nti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nti OCA], [https://pdbe.org/1nti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nti RCSB], [https://www.ebi.ac.uk/pdbsum/1nti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nti ProSAT]</span></td></tr>
{{STRUCTURE_1nti|  PDB=1nti  |  SCENE=  }}
</table>
 
== Function ==
===RDC-refined NMR structure of bovine Acyl-coenzyme A Binding Protein, ACBP===
[https://www.uniprot.org/uniprot/ACBP_BOVIN ACBP_BOVIN] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.<ref>PMID:11491287</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_8358232}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 8358232 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1nti_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_8358232}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nti ConSurf].
[[1nti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTI OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:8358232</ref><ref group="xtra">PMID:8503960</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Kragelund, B B.]]
[[Category: Large Structures]]
[[Category: Lerche, M H.]]
[[Category: Kragelund BB]]
[[Category: Poulsen, F M.]]
[[Category: Lerche MH]]
[[Category: Redfield, C.]]
[[Category: Poulsen FM]]
[[Category: Acbp family]]
[[Category: Redfield C]]
[[Category: Four-helix-bundle]]
[[Category: Lipid binding protein]]

Latest revision as of 08:53, 10 April 2024

RDC-refined NMR structure of bovine Acyl-coenzyme A Binding Protein, ACBP

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