2bcw: Difference between revisions

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[[Image:2bcw.png|left|200px]]


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==Coordinates of the N-terminal domain of ribosomal protein L11,C-terminal domain of ribosomal protein L7/L12 and a portion of the G' domain of elongation factor G, as fitted into cryo-em map of an Escherichia coli 70S*EF-G*GDP*fusidic acid complex==
The line below this paragraph, containing "STRUCTURE_2bcw", creates the "Structure Box" on the page.
<SX load='2bcw' size='340' side='right' viewer='molstar' caption='[[2bcw]], [[Resolution|resolution]] 11.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2bcw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcw OCA], [https://pdbe.org/2bcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcw RCSB], [https://www.ebi.ac.uk/pdbsum/2bcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcw ProSAT]</span></td></tr>
{{STRUCTURE_2bcw|  PDB=2bcw  |  SCENE=  }}
</table>
 
== Function ==
===Coordinates of the N-terminal domain of ribosomal protein L11,C-terminal domain of ribosomal protein L7/L12 and a portion of the G' domain of elongation factor G, as fitted into cryo-em map of an Escherichia coli 70S*EF-G*GDP*fusidic acid complex===
[https://www.uniprot.org/uniprot/RL7_ECOLI RL7_ECOLI] Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation.[HAMAP-Rule:MF_00368]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcw_consurf.spt"</scriptWhenChecked>
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bcw ConSurf].
[[2bcw]] is a 3 chain structure of [[Ribosomal protein L11]] and [[Ribosomal protein L7]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCW OCA].  
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==See Also==
==See Also==
*[[Ribosomal protein L11]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
*[[Ribosomal protein L7]]
*[[Ribosomal protein L11 3D structures|Ribosomal protein L11 3D structures]]
 
*[[Ribosomal protein L7/L12|Ribosomal protein L7/L12]]
==Reference==
__TOC__
<ref group="xtra">PMID:16337596</ref><ref group="xtra">PMID:10338213</ref><ref group="xtra">PMID:3309338</ref><ref group="xtra">PMID:8070397</ref><references group="xtra"/>
</SX>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Agrawal, R K.]]
[[Category: Agrawal RK]]
[[Category: Datta, P P.]]
[[Category: Datta PP]]
[[Category: Frank, J.]]
[[Category: Frank J]]
[[Category: Qi, L.]]
[[Category: Qi L]]
[[Category: Sharma, M R.]]
[[Category: Sharma MR]]
[[Category: Components involved in interaction between ef-g and l7/l12 stalk base of the ribosome]]