3r0i: Difference between revisions

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'''Unreleased structure'''


The entry 3r0i is ON HOLD
==IspC in complex with an N-methyl-substituted hydroxamic acid==
<StructureSection load='3r0i' size='340' side='right'caption='[[3r0i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3r0i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R0I FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C0K:{(1S)-1-(3,4-DIFLUOROPHENYL)-4-[HYDROXY(METHYL)AMINO]-4-OXOBUTYL}PHOSPHONIC+ACID'>C0K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0i OCA], [https://pdbe.org/3r0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0i RCSB], [https://www.ebi.ac.uk/pdbsum/3r0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DXR_ECOLI DXR_ECOLI] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).[HAMAP-Rule:MF_00183]


Authors: Behrendt, C.T., Kunfermann, A., Illarionova, V., Matheeussen, A., Pein, M.K., Graewert, T., Bacher, A., Eisenreich, W., Illarionov, B., Fischer, M., Maes, L., Groll, M., Kurz, T.
==See Also==
 
*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
Description: IspC in complex with an N-methyl-substituted hydroxamic acid
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Bacher A]]
[[Category: Behrendt CT]]
[[Category: Eisenreich W]]
[[Category: Fischer M]]
[[Category: Graewert T]]
[[Category: Groll M]]
[[Category: Illarionov B]]
[[Category: Illarionova V]]
[[Category: Kunfermann A]]
[[Category: Kurz T]]
[[Category: Maes L]]
[[Category: Matheeussen A]]
[[Category: Pein MK]]
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