Barnase: Difference between revisions
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Michal Harel (talk | contribs) New page: left|200px|thumb|Crystal Structure of Barnase [[1bni]] {{STRUCTURE_1bni| PDB=1bni | SIZE=300| SCENE= |right|CAPTION=Barnase 1bni }} '''Barnase'''(BA) is a bacteri... |
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<StructureSection load='1brn' size='350' side='right' scene='44/442736/Cv/2' caption='Barnase complex with tetranucleotide (PDB code [[1brn]])'> | |||
== Function == | |||
'''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial [[ribonuclease]] synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. <ref>PMID:8110767</ref> The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | |||
== | == Relevance == | ||
BA structure was used extensively for studying protein folding. | |||
== Structural highlights == | |||
BA hydrolyzes RNA at GpN sites where the <scene name='44/442736/Cv/4'>active site positively charged Lys and Arg coordinate the RNA phosphate group</scene> (Lys and Arg are in magenta). | |||
== 3D Structures of Barnase == | |||
[[Barnase 3D structures]] | |||
[[ | |||
</StructureSection> | |||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 14:37, 20 February 2022
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