1e9s: Difference between revisions

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[[Image:1e9s.gif|left|200px]]<br />
<applet load="1e9s" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1e9s, resolution 2.50&Aring;" />
'''BACTERIAL CONJUGATIVE COUPLING PROTEIN TRWBDELTAN70. UNBOUND MONOCLINIC FORM.'''<br />


==Overview==
==Bacterial conjugative coupling protein TrwBdeltaN70. Unbound monoclinic form.==
The transfer of DNA across membranes and between cells is a central, biological process; however, its molecular mechanism remains unknown. In, prokaryotes, trans-membrane passage by bacterial conjugation, is the main, route for horizontal gene transfer. It is the means for rapid acquisition, of new genetic information, including antibiotic resistance by pathogens., Trans-kingdom gene transfer from bacteria to plants or fungi and even, bacterial sporulation are special cases of conjugation. An integral, membrane DNA-binding protein, called TrwB in the Escherichia coli R388, conjugative system, is essential for the conjugation process. This large, multimeric protein is responsible for recruiting the relaxosome, DNA-protein complex, and participates in the transfer of a single DNA, strand ... [[http://ispc.weizmann.ac.il/pmbin/getpm?11214325 (full description)]]
<StructureSection load='1e9s' size='340' side='right'caption='[[1e9s]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1e9s]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E9S FirstGlance]. <br>
1E9S is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Structure known Active Site: NBS. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E9S OCA]].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9s OCA], [https://pdbe.org/1e9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e9s RCSB], [https://www.ebi.ac.uk/pdbsum/1e9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e9s ProSAT]</span></td></tr>
==Reference==
</table>
The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase., Gomis-Ruth FX, Moncalian G, Perez-Luque R, Gonzalez A, Cabezon E, de la Cruz F, Coll M, Nature. 2001 Feb 1;409(6820):637-41. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11214325 11214325]
== Function ==
[https://www.uniprot.org/uniprot/Q04230_ECOLX Q04230_ECOLX]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/1e9s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e9s ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Cabezon, E.]]
[[Category: Cabezon E]]
[[Category: Coll, M.]]
[[Category: Coll M]]
[[Category: Cruz, F.De.La.]]
[[Category: Gomis-Rueth FX]]
[[Category: Gomis-Rueth, F.X.]]
[[Category: Moncalian G]]
[[Category: Moncalian, G.]]
[[Category: De la Cruz F]]
[[Category: bacterial conjugation]]
[[Category: coupling protein]]
[[Category: f1-atpase-like quaternary structure]]
[[Category: ring helicases]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:50:58 2007''

Latest revision as of 10:00, 20 March 2024

Bacterial conjugative coupling protein TrwBdeltaN70. Unbound monoclinic form.

1e9s, resolution 2.50Å

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