3raj: Difference between revisions
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New page: '''Unreleased structure''' The entry 3raj is ON HOLD Authors: Zhang, H., Lee, H.C., Hao, Q. Description: Crystal structure of human CD38 in complex with the Fab fragment of antibody HB... |
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==Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7== | |||
<StructureSection load='3raj' size='340' side='right'caption='[[3raj]], [[Resolution|resolution]] 3.04Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3raj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.044Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3raj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3raj OCA], [https://pdbe.org/3raj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3raj RCSB], [https://www.ebi.ac.uk/pdbsum/3raj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3raj ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. | |||
==See Also== | |||
*[[Antibody 3D structures|Antibody 3D structures]] | |||
*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] | |||
*[[3D structures of non-human antibody|3D structures of non-human antibody]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Hao Q]] | |||
[[Category: Lee HC]] | |||
[[Category: Zhang H]] | |||
Latest revision as of 17:15, 1 November 2023
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
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