3qwp: Difference between revisions

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[[Image:3qwp.jpg|left|200px]]


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==Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1==
The line below this paragraph, containing "STRUCTURE_3qwp", creates the "Structure Box" on the page.
<StructureSection load='3qwp' size='340' side='right'caption='[[3qwp]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3qwp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3qwp|  PDB=3qwp  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwp OCA], [https://pdbe.org/3qwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwp RCSB], [https://www.ebi.ac.uk/pdbsum/3qwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwp ProSAT]</span></td></tr>
 
</table>
===Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1===
== Function ==
 
[https://www.uniprot.org/uniprot/SMYD3_HUMAN SMYD3_HUMAN] Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.<ref>PMID:15235609</ref> <ref>PMID:22419068</ref>
 
== References ==
==About this Structure==
<references/>
[[3qwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWP OCA].  
__TOC__
[[Category: Histone-lysine N-methyltransferase]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Dombrovski, L.]]
[[Category: Bountra C]]
[[Category: Dong, A.]]
[[Category: Dombrovski L]]
[[Category: Edwards, A M.]]
[[Category: Dong A]]
[[Category: Li, Y.]]
[[Category: Edwards AM]]
[[Category: Min, J.]]
[[Category: Li Y]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Min J]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Wernimont, A.]]
[[Category: Wernimont A]]
[[Category: Wu, H.]]
[[Category: Wu H]]
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