2nuz: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /><applet load="2nuz" size="350" color="white" frame="true" align="right" spinBox="true" caption="2nuz, resolution 1.85Å" /> '''crystal structure of... |
No edit summary |
||
| (16 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==crystal structure of alpha spectrin SH3 domain measured at room temperature== | ||
<StructureSection load='2nuz' size='340' side='right'caption='[[2nuz]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2nuz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NUZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nuz OCA], [https://pdbe.org/2nuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nuz RCSB], [https://www.ebi.ac.uk/pdbsum/2nuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nuz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nuz_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nuz ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Spectrin 3D structures|Spectrin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Agarwal | [[Category: Agarwal V]] | ||
[[Category: Chevelkov | [[Category: Chevelkov V]] | ||
[[Category: Diehl | [[Category: Diehl A]] | ||
[[Category: Faelber | [[Category: Faelber K]] | ||
[[Category: Hologne | [[Category: Hologne M]] | ||
[[Category: Oschkinat | [[Category: Oschkinat H]] | ||
[[Category: Reif | [[Category: Reif B]] | ||
