Dynactin: Difference between revisions

Latest revision as of 09:12, 4 May 2025

spinqualitylabelsall models

Dynactin subunit 1 CAP-Gly domain (magenta and yellow) complex with the C-terminal domain of human EB1 (cyan and green) and chloride ion 2hl5

Drag the structure with the mouse to rotate

@@ Line 1: / Line 1: @@
+<StructureSection load='2hl5' size='350' side='right' scene='44/444636/Cv/1' caption='Dynactin subunit 1 CAP-Gly domain (magenta and yellow) complex with the C-terminal domain of human EB1 (cyan and green) and chloride ion [[2hl5]]'>
-[[Image:2hkq.png|left|200px|thumb|Crystal Structure of Dynactin, [[2hkq]]]]
+__TOC__
-{{STRUCTURE_2hkq|  PDB=2hkq  | SIZE=300|  |right|CAPTION=Dynactin subunit 1 CAP-Gly domain complex with protein linker, [[2hkq]] }}
-'''Dynactin''' (DCTN) is a multi-subunit protein which modulates the binding of dynein to cell organelles which are to be transported along microtubules.
+== Function ==
-{{TOC limit|limit=2}}
+'''Dynactin''' (DCTN) is a multi-subunit protein which modulates the binding of dynein to cell organelles which are to be transported along microtubules.<ref>PMID:1836789</ref> See also [[CAP-Gly domain]].
+== Disease ==
+Mutant dynactin was found in motor neuron disease.<ref>PMID:12627231</ref>
+== Structural highlights ==
+<scene name='44/444636/Cv/3'>Dynactin subunit 1 CAP-Gly domain with the C-terminal domain of human EB1</scene> ([[2hl5]]).<ref>PMID:16949363</ref>
 == 3D Structures of Dynactin ==
+[[Dynactin 3D structures]]
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+== References ==
+<references/>
+</StructureSection>
+[[Category:Topic Page]]