3p5j: Difference between revisions

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[[Image:3p5j.png|left|200px]]


<!--
==The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease==
The line below this paragraph, containing "STRUCTURE_3p5j", creates the "Structure Box" on the page.
<StructureSection load='3p5j' size='340' side='right'caption='[[3p5j]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3p5j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P5J FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p5j OCA], [https://pdbe.org/3p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p5j RCSB], [https://www.ebi.ac.uk/pdbsum/3p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p5j ProSAT]</span></td></tr>
{{STRUCTURE_3p5j|  PDB=3p5j  |  SCENE=  }}
</table>
 
== Function ==
===The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease===
[https://www.uniprot.org/uniprot/RNH2A_MOUSE RNH2A_MOUSE] Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.<ref>PMID:19923215</ref>
 
 
<!--
The line below this paragraph, {{ABSTRACT_PUBMED_21177854}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21177854 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_21177854}}
 
==About this Structure==
[[3p5j]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5J OCA].  


==See Also==
==See Also==
*[[Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:21177854</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Ribonuclease H]]
[[Category: Bubeck D]]
[[Category: Bubeck, D.]]
[[Category: Graham SC]]
[[Category: Graham, S C.]]
[[Category: Jones EY]]
[[Category: Jones, E Y.]]

Latest revision as of 10:38, 21 February 2024

The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease

3p5j, resolution 2.90Å

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