3mji: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
The | ==Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor== | ||
<StructureSection load='3mji' size='340' side='right'caption='[[3mji]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3mji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mji OCA], [https://pdbe.org/3mji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mji RCSB], [https://www.ebi.ac.uk/pdbsum/3mji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mji ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase. | |||
==See Also== | |||
*[[Penicillin acylase|Penicillin acylase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Lysinibacillus sphaericus]] | |||
[[Category: Dodson GG]] | |||
[[Category: Murshudov GN]] | |||
[[Category: Pathak MC]] | |||
[[Category: Suresh CG]] | |||
Latest revision as of 08:48, 7 February 2024
Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor
| ||||||||||||
